Spatiotemporal mapping of auditory onsets during speech production

Read the paper: Kurteff GL, Field AM, Asghar S, Tyler-Kabara EC, Clarke D, Weiner HL, Anderson AE, Watrous AJ, Buchanan RJ, Modur PN, Hamilton LS. 2024 Oct 22.

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Brain Viewer Tour

This is an interactive viewer to accompany our paper Processing of auditory feedback in perisylvian and insular cortex. In our study, participants read sentences aloud and listened to playback of their own voice.

Schematic of reading + playback audio. Participants first heard a click, then read sentences aloud while hearing their own voice. After a second click sound, their own voice was played back to them.

We recorded neural data from intracranial electrodes from patients with epilepsy as they performed this task.

Research performed by Garret Lynn Kurteff, Alyssa M. Field, Saman Asghar, Elizabeth C. Tyler-Kabara, Dave Clarke, Howard L. Weiner, Anne E. Anderson, Andrew J. Watrous, Robert J. Buchanan, Pradeep N. Modur, Liberty S. Hamilton.

Viewer created by Liberty Hamilton using 3js

Consistent and Inconsistent

Trials were split up into consistent and inconsistent playback, where consistent matched exactly what they had said in that trial, and inconsistent playback would play audio of a previous sentence. In all cases, the audio is spoken by the patient.

Schematic of consistent vs. inconsistent playback

Choose Participant →

You can use this viewer to click on individual electrodes and see their responses during different conditions in the speaking and listening task. You can view all electrodes projected onto a single atlas brain, or you can choose to view individual participants by choosing from the dropdown menus at the top right.

Device lines will draw lines between electrode channels that are part of the same implanted sEEG device

Choose Response Type →

Click on electrodes to view their high gamma evoked potential responses. For Response Type you can choose between several options.

Electrode Information

When you click on an electrode, you will also see information about the participant ID, electrode name (given by the clinical montage), and anatomical area.

Onset suppression during speaking

This electrode shows strong onset responses during listening that are suppressed during speaking.

End of Tutorial

You're ready to explore the brain viewer on your own! Try clicking on electrodes, changing the angle of view, or trying different colors and transparencies for the brain. Have fun!